For U.S. Residents Only Synvisc-One

Meet patients who fought back against osteoarthritis knee pain.

Charlotte R, 61, Michigan 

“My husband and I used to walk a lot when we traveled, but because my knee would start hurting too much too quickly, we couldn’t even go to museums anymore.”

Can’t get away  

Like many knee osteoarthritis sufferers, pain became the norm for Charlotte. But she still led a full life. She traveled often, enjoyed walking and rode her exercise bike whenever she could. Over time, however, the pain became too much.

“My husband and I used to walk a lot when we traveled, but because my knee would start hurting too much too quickly, we couldn’t even go to museums anymore. I also worked installing and repairing computers, which meant crawling around on the floor for cords and things like that. It got so difficult for me.”

The big turning point for Charlotte came when her primary care doctor sent her to an orthopaedic surgeon who told her she had osteoarthritis of the knee.

If at first you don’t succeed… 

The orthopaedic surgeon recommended a total knee replacement. Despite her long history of osteoarthritis knee pain, Charlotte wasn’t ready for such an extreme measure. Instead, she sought a second opinion and went to another specialist.

While in the waiting room, she read a brochure about Synvisc-One® (hylan G-F 20). “Then the doctor came in, saw that we were reading the brochure and said that’s what he was going to recommend because my other knee osteoarthritis treatments hadn’t worked.”

Charlotte had a great experience with Synvisc-One, starting with the injection itself. “From the time the doctor walked in to prep me, I was in and out in seven minutes.”

Going, going, gone 

Synvisc-One helped Charlotte find osteoarthritis knee pain relief, which had a tremendous impact on her life. She’s walking more, and she’s going to ballgames and museums again.

Charlotte recently tested her driving knee on a trek to Wisconsin — something she never would have been able to do with osteoarthritis knee pain. “It’s a 485-mile drive each way. But I didn’t have problems with osteoarthritis knee pain like I did before Synvisc-One. ”

PLEASE NOTE: This article is a testimonial of one patient’s story and her experience with Synvisc-One. Individual results may vary.

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Indication

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One

Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Allergic reactions, some which can be potentially severe, have been reported during the use of Synvisc-One. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, and should be used with caution when there is swelling of the legs due to problems with venous stasis or lymphatic drainage.

Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

Synvisc-One has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

 

View the Complete Prescribing Information for Synvisc-One

 

Indication

SYNVISC® (hylan G-F 20) is used to relieve knee pain due to osteoarthritis (OA). It is for patients who do not get enough relief from simple painkillers such as acetaminophen, or from exercise and physical therapy.

Important Safety Information for SYNVISC

Before trying SYNVISC, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Serious allergic reactions have been reported. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

SYNVISC is only for injection into the knee, performed by a doctor or other qualified health care professional. SYNVISC has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds - such as feathers, eggs or poultry - or if your leg is swollen or infected.

SYNVISC has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after SYNVISC include pain, swelling, heat, redness, and/or fluid buildup in or around the knee. These reactions were generally mild and did not last long, but in rare occasions these side effects were more severe. The most commonly occurring adverse events outside of the injected knee were rash, fever, nausea, and headache.

View the Complete Prescribing Information for SYNVISC

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Important Safety Information: SYNVISC and Synvisc-One are contraindicated in patients with known hypersensitivity to hyaluronan products or patients with infections in or around the target knee.