For U.S. Residents Only Synvisc-One

Meet patients who fought back against osteoarthritis knee pain.

Mike C, 50, New Hampshire

“It was a lot more difficult to run the farm. Getting up and down off equipment, all the heavy lifting. You need your knees. The next morning I’d try to get out of bed and — ouch.”

Pain outside and in

Six years ago, Mike was doing what many active, nature-loving people do. Hunting. Fishing. Enjoying his farm and horses. That is, until he started to experience knee pain.

“It was a lot more difficult to run the farm. Getting up and down off equipment, all the heavy lifting. You need your knees. The next morning I’d try to get out of bed and — ouch.”

As a 28-year police veteran, Mike also spent a lot of time behind his desk. Sometimes just sitting for a few hours would cause his knee pain to flare up. With knee pain getting in the way of both his work and leisure time, Mike knew it was time to see a doctor.

Getting motivated

Mike’s doctor diagnosed him with mild knee osteoarthritis. Although the X-ray said mild, the pain was anything but — with over-the-counter pain relievers doing little to help.

The doctor suggested that Mike consider a more long-term treatment option like Synvisc-One® (hylan G-F 20). So he did. “I had my injection and the osteoarthritis knee pain reduction was significant. Being able to do all my activities without taking a handful of ibuprofen every few hours is a big plus for me.”

“When it hurts to exercise, you just don’t do it. So anything you can do to minimize osteoarthritis knee pain is going to encourage you to make an effort to exercise. Before Synvisc-One, the pain would deter me from doing any more than I absolutely needed to.”

Now Mike is getting back to some of his favorite activities. “I intend to do some hunting this year, which I haven’t been able to do in probably the last three years.”

Spreading the word

Since Mike was treated with Synvisc-One, he’s been excited to spread word of his success.

He has some advice for people who are nervous about injections. “That’s one of the things that keeps people from talking to their doctor about it. Anyone that’s had an injection assumes Synvisc-One is going to be painful. But the Synvisc-One injection didn’t hurt — and it gave me relief for a lot longer.”

PLEASE NOTE: This article is a testimonial of one patient’s story and his experience with Synvisc-One. Individual results may vary.

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Indication

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One

Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Allergic reactions, some which can be potentially severe, have been reported during the use of Synvisc-One. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, and should be used with caution when there is swelling of the legs due to problems with venous stasis or lymphatic drainage.

Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

Synvisc-One has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

 

View the Complete Prescribing Information for Synvisc-One

 

Indication

SYNVISC® (hylan G-F 20) is used to relieve knee pain due to osteoarthritis (OA). It is for patients who do not get enough relief from simple painkillers such as acetaminophen, or from exercise and physical therapy.

Important Safety Information for SYNVISC

Before trying SYNVISC, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Serious allergic reactions have been reported. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

SYNVISC is only for injection into the knee, performed by a doctor or other qualified health care professional. SYNVISC has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds - such as feathers, eggs or poultry - or if your leg is swollen or infected.

SYNVISC has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after SYNVISC include pain, swelling, heat, redness, and/or fluid buildup in or around the knee. These reactions were generally mild and did not last long, but in rare occasions these side effects were more severe. The most commonly occurring adverse events outside of the injected knee were rash, fever, nausea, and headache.

View the Complete Prescribing Information for SYNVISC

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Important Safety Information: SYNVISC and Synvisc-One are contraindicated in patients with known hypersensitivity to hyaluronan products or patients with infections in or around the target knee.